From NKAA, Notable Kentucky African Americans Database (main entry)
Slave Deaths due to Cholera, 1850 U.S. Federal Census Mortality ScheduleThe federal mortality schedules, for which data were first collected in 1849, included the cholera deaths of slaves, many listed by name. Prior to 1870, it had been the free African Americans who were listed in the U.S. Federal Census by name, while slaves were listed in the Slave Schedules by sex and age under the names of their owners. The mortality schedules were published 1850-1880, and the number of overall deaths in the U.S. were under reported in the data collection. There were hundreds of deaths in Kentucky due to cholera before, after, and during the year 1850. Cholera is an infection of the small intestine caused by the consumption of food or water contaminated with the bacterium Vibrio cholerae (more info at MedlinePlus).
In 1850, as the U.S. was striving for better public health measures, doctors were still searching for the exact cause of the disease, how it was transferred and how it could be treated and prevented. A nationwide cholera epidemic had taken place in 1848-49. Former U.S. President James K. Polk died of cholera in 1849 after a visit to Louisiana. His presidency was followed by that of 12th U.S. President Zachary Taylor, who died of cholera in 1850. [He was born in Virginia and grew up in Kentucky.] Mary A. Fillmore, daughter of the 13th U.S. President, Millard Fillmore, died of cholera in 1854. Lucy Ware Webb Hayes (whitehouse.gov), the wife of 19th U.S. President Rutherford B. Hayes, lost her father to cholera in 1833 when he came to his hometown, Lexington, KY, to free the slaves that he had recently inherited. In addition to Dr. James Webb, his mother, father, and brother also died of cholera.
After the 1830s cholera epidemic, there were publications written for southerns on the medical treatment of cholera in slaves. With the second epidemic in the late 1840s, there was a request for a publication on what was considered an effective treatment by Dr. C. B. New. In 1850 he published Cholera: observations on the management of cholera on plantations, and method of treating the disease [available online at US. National Library of Medicine]. Included in the 1850 U.S. Federal Census Mortality Schedule are 71 black slaves in Kentucky who died of cholera, most from Scott, Warren, and Woodford Counties; the schedule also lists the death of seven Kelly slaves in Warren County, in June 1850. There were also 16 mulatto slave deaths in Scott, Shelby, Spencer, Union and Warren Counties. S. M. Young, a free mulatto woman from Scott County, also died of cholera in 1850.
For more see The Health of Slaves on Southern Plantations, by W. D. Postell; Observations on the epidemic now prevailing in the City of New-York, by C. C. Yates [available full-text at Google Book Search]; Cholera; its pathology, diagnosis, and treatment, by William Story [available full-text at Google Book Search]; T. L. Savitt's Medicine and Slavery; and Finding Answers in U.S. Census Records, by L. D. Szucs and M. Wright.